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Activity title

Improving the Understanding of Risks from Exposure to Munition Combustion Products

Activity Reference

AVT-363

Panel

AVT

Security Classification

NATO UNCLASSIFIED

Status

Active

Activity type

RTG

Start date

2022-01-01T00:00:00Z

End date

2024-12-31T00:00:00Z

Keywords

Combustion products, exposure, hazards, risks, small caliber munitions, toxicity values

Background

Over the years the awareness has increased regarding potential adverse health effects of exposure of military personnel to chemicals. Exposures can adversely affect the health of warfighters, directly affecting military readiness and influence results on the battlefield. These chemicals may originate from various sources, among others from the use of ammunition. In contrast to exposure to chemicals from other sources, firing ammunition often results in concentrated, pulsed, repetitive, exposures that are challenging to assess. This questions the use of current occupational health exposure guidelines that may not suitable for evaluating the toxicological hazards when firing ammunition. The recent RTG AVT-277 evaluated the limits of currently used approaches to estimate hazards from firing ammunition. One of the conclusions of this RTG was that there is no uniform approach to perform the qualitative and quantitative measurement of emission products at the breathing zone when firing ammunition in a pulsed manner. These measurements are important to get a better understanding of the parameters influencing the formation and final composition of emitted products. This knowledge is essential for the development of model that can predict the emissions from weapon/ammunition combinations. This RTG proposes to advance our understanding step towards the final goal of performing an adequate prediction of the chemical hazards when using ammunition and even performing a representable risk assessment.

Objectives

Within this RTG we aim to: - Identify the components of interest in emissions within the exposure pathway(s) of interest, - Identify parameters that primarily influence the formation of toxic emission products from small arms use, - Develop an outline for a universal approach for comparing emissions from various weapon-munition combinations to submit to subgroup AC-326 for a STANAG/AOP (will result in a separate specialists group within AVT), - Evaluate the usability of distribution / dispersion models to better identify peaks in exposure at the breathing zone, - Evaluate the kinetic importance of pulsed-high exposures in the manifestation of adverse effects by comparing exposure to distribution, metabolism and excretion (e.g. use of PBPK models), - Derive soldier-specific toxicity values for specific time periods (short) and repetitive exposures for components with reversible (e.g., CO) and irreversible (NO2) effects, and, - Make recommendations for improving exposure estimates.

Topics

Within this RTG we would like to address the following topics: - Identifying parameters of influence on the emission products (weapon/munition/environmental) - Evaluation of distribution / dispersion models - Evaluate the applicability of existing soldier specific toxicity values for specific time periods (short) and repetitive exposures (via use of Physiologically based pharmacokinetic (PBPK) modelling) - Propose a universal approach for comparing emissions from various weapon-munition combinations. Make preparations for a STANAG/AOP

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